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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADA
All Species:
14.85
Human Site:
T318
Identified Species:
29.7
UniProt:
P00813
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00813
NP_000013.2
363
40764
T318
T
K
R
D
M
G
F
T
E
E
E
F
K
R
L
Chimpanzee
Pan troglodytes
XP_001144517
363
40678
T318
T
K
R
D
M
G
F
T
E
E
E
F
K
R
L
Rhesus Macaque
Macaca mulatta
XP_001109908
572
62188
T527
T
K
R
D
M
G
F
T
E
E
E
F
K
R
L
Dog
Lupus familis
XP_534428
362
41003
T317
T
K
Q
G
M
D
F
T
E
E
E
F
K
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P03958
352
39973
Y308
K
S
T
L
D
T
D
Y
Q
M
T
K
K
D
M
Rat
Rattus norvegicus
Q920P6
352
39881
Y308
K
S
T
V
D
T
D
Y
Q
M
V
K
K
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508594
308
34510
H264
R
L
K
A
E
N
M
H
F
Q
V
C
P
W
S
Chicken
Gallus gallus
Q5ZKP6
357
40660
K311
D
K
D
Y
G
I
V
K
E
Y
M
D
F
T
E
Frog
Xenopus laevis
Q6GP70
358
40658
M314
Y
S
I
A
V
Q
H
M
G
F
T
E
D
E
F
Zebra Danio
Brachydanio rerio
Q6DG22
359
40825
M315
Y
E
V
V
Q
K
Y
M
D
F
T
E
E
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501087
391
43657
F336
S
R
D
D
P
T
C
F
D
N
S
M
L
S
E
Sea Urchin
Strong. purpuratus
XP_785367
391
43729
Q347
N
T
M
E
S
E
F
Q
L
A
K
T
Y
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
61.3
85.6
N.A.
80.9
83.1
N.A.
58.9
65.5
69.1
64.1
N.A.
N.A.
N.A.
31.4
35.8
Protein Similarity:
100
99.4
62.7
91.4
N.A.
90.6
91.4
N.A.
68.3
79
81.8
78.5
N.A.
N.A.
N.A.
50.3
54.4
P-Site Identity:
100
100
100
80
N.A.
6.6
6.6
N.A.
0
13.3
0
0
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
20
20
N.A.
13.3
13.3
6.6
26.6
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% C
% Asp:
9
0
17
34
17
9
17
0
17
0
0
9
9
17
9
% D
% Glu:
0
9
0
9
9
9
0
0
42
34
34
17
9
17
17
% E
% Phe:
0
0
0
0
0
0
42
9
9
17
0
34
9
9
17
% F
% Gly:
0
0
0
9
9
25
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
42
9
0
0
9
0
9
0
0
9
17
50
0
0
% K
% Leu:
0
9
0
9
0
0
0
0
9
0
0
0
9
0
34
% L
% Met:
0
0
9
0
34
0
9
17
0
17
9
9
0
0
17
% M
% Asn:
9
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
9
0
9
9
0
9
17
9
0
0
0
0
0
% Q
% Arg:
9
9
25
0
0
0
0
0
0
0
0
0
0
34
0
% R
% Ser:
9
25
0
0
9
0
0
0
0
0
9
0
0
9
9
% S
% Thr:
34
9
17
0
0
25
0
34
0
0
25
9
0
9
0
% T
% Val:
0
0
9
17
9
0
9
0
0
0
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
17
0
0
9
0
0
9
17
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _